Protein Info for b4356 in Escherichia coli BW25113

Name: yjiZ
Annotation: predicted transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 39 to 56 (18 residues), see Phobius details amino acids 76 to 95 (20 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 170 to 192 (23 residues), see Phobius details amino acids 198 to 216 (19 residues), see Phobius details amino acids 260 to 279 (20 residues), see Phobius details amino acids 299 to 321 (23 residues), see Phobius details amino acids 333 to 352 (20 residues), see Phobius details amino acids 358 to 384 (27 residues), see Phobius details amino acids 396 to 415 (20 residues), see Phobius details amino acids 421 to 442 (22 residues), see Phobius details PF07690: MFS_1" amino acids 47 to 408 (362 residues), 202.6 bits, see alignment E=4.4e-64

Best Hits

Swiss-Prot: 100% identical to LGOT_ECOLI: Probable L-galactonate transporter (lgoT) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b4356)

MetaCyc: 100% identical to galactonate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-227

Predicted SEED Role

"D-galactonate transporter" in subsystem D-galactonate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P39398 at UniProt or InterPro

Protein Sequence (453 amino acids)

>b4356 predicted transporter (NCBI) (Escherichia coli BW25113)
MEKENITIDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSS
LSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLF
QAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVA
VSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAA
IPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVL
LIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHS
FRLALIICGCVTAAGALAYIFLVRQPINDPRKD