Protein Info for b4096 in Escherichia coli BW25113

Name: phnL
Annotation: carbon-phosphorus lyase complex subunit (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 TIGR02324: phosphonate C-P lyase system protein PhnL" amino acids 1 to 218 (218 residues), 369.7 bits, see alignment E=2.4e-115 PF00005: ABC_tran" amino acids 24 to 178 (155 residues), 113.9 bits, see alignment E=9.3e-37

Best Hits

Swiss-Prot: 100% identical to PHNL_ECOLI: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL (phnL) from Escherichia coli (strain K12)

KEGG orthology group: K05780, putative phosphonate transport system ATP-binding protein (inferred from 100% identity to eco:b4096)

MetaCyc: 100% identical to ATP-binding cassette protein PhnL (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Phosphonates transport ATP-binding protein PhnL" in subsystem Alkylphosphonate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P16679 at UniProt or InterPro

Protein Sequence (226 amino acids)

>b4096 carbon-phosphorus lyase complex subunit (NCBI) (Escherichia coli BW25113)
MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSGSGKSTLLRSLYANYLP
DEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVIPRISALEVVMQPLLDTGV
PREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNIARGFIVDYPILLLDEPTASL
DAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADRLHPMGASS