Protein Info for b4085 in Escherichia coli BW25113

Name: alsE
Annotation: allulose-6-phosphate 3-epimerase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00834: Ribul_P_3_epim
  • amino acids 2 to 196 (195 residues), 204.9 bits, E=4.5e-65

Best Hits

Swiss-Prot: 100% identical to ALSE_ECOLI: D-allulose-6-phosphate 3-epimerase (alsE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b4085)

MetaCyc: 100% identical to D-allulose-6-phosphate 3-epimerase (Escherichia coli K-12 substr. MG1655)
5.1.3.-

Predicted SEED Role

"D-allulose-6-phosphate 3-epimerase (EC 5.1.3.-)" (EC 5.1.3.-)

MetaCyc Pathways

• D-allose degradation (3/3 steps found)

KEGG Metabolic Maps

• Nucleotide sugars metabolism
• Polyketide sugar unit biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 5.1.3.-

Use Curated BLAST to search for 5.1.3.-

Sequence Analysis Tools

See P32719 at UniProt or InterPro

Protein Sequence (231 amino acids)

>b4085 allulose-6-phosphate 3-epimerase (NCBI) (Escherichia coli BW25113)
MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLATKPL
DCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEIRRHDMKVGLILNPETPVE
AMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAWREREGLEYEIEVDGSCNQAT
YEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA