Protein Info for b4084 in Escherichia coli BW25113

Name: alsK
Annotation: D-allose kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF00480: ROK" amino acids 9 to 298 (290 residues), 323.3 bits, see alignment E=8.5e-101

Best Hits

Swiss-Prot: 100% identical to ALSK_ECOLI: D-allose kinase (alsK) from Escherichia coli (strain K12)

KEGG orthology group: K00881, allose kinase [EC: 2.7.1.55] (inferred from 100% identity to eco:b4084)

MetaCyc: 100% identical to D-allose kinase (Escherichia coli K-12 substr. MG1655)
Allose kinase. [EC: 2.7.1.55]

Predicted SEED Role

"D-allose kinase (EC 2.7.1.55)" in subsystem D-allose utilization (EC 2.7.1.55)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.55

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P32718 at UniProt or InterPro

Protein Sequence (309 amino acids)

>b4084 D-allose kinase (NCBI) (Escherichia coli BW25113)
MQKQHNVVAGVDMGATHIRFCLRTAEGETLHCEKKRTAEVIAPGLVSGIGEMIDEQLRRF
NARCHGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKLENTLNCPVEFSRDVNLQL
SWDVVENRLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGVAGELGHIPLGDMTQHCACGN
PGCLETNCSGMALRRWYEQQPRNYPLRDLFVHAENAPFVQSLLENAARAIATSINLFDPD
AVILGGGVMDMPAFPRETLVAMTQKYLRRPLPHQVVRFIAASSSDFNGAQGAAILAHQRF
LPQFCAKAP