Protein Info for b3917 in Escherichia coli BW25113

Name: sbp
Annotation: sulfate transporter subunit (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR00971: sulfate ABC transporter, sulfate-binding protein" amino acids 12 to 326 (315 residues), 636.1 bits, see alignment E=4.9e-196 PF01547: SBP_bac_1" amino acids 32 to 272 (241 residues), 70.5 bits, see alignment E=5e-23 PF13531: SBP_bac_11" amino acids 42 to 280 (239 residues), 144.2 bits, see alignment E=1.1e-45 PF13416: SBP_bac_8" amino acids 87 to 281 (195 residues), 36 bits, see alignment E=1.3e-12 PF13343: SBP_bac_6" amino acids 129 to 297 (169 residues), 40.5 bits, see alignment E=4.7e-14

Best Hits

Swiss-Prot: 100% identical to SUBI_ECOLI: Sulfate-binding protein (sbp) from Escherichia coli (strain K12)

KEGG orthology group: K02048, sulfate transport system substrate-binding protein (inferred from 100% identity to eco:b3917)

MetaCyc: 100% identical to sulfate/thiosulfate ABC transporter periplasmic binding protein Sbp (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate-binding protein Sbp"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AG78 at UniProt or InterPro

Protein Sequence (329 amino acids)

>b3917 sulfate transporter subunit (NCBI) (Escherichia coli BW25113)
MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFSAHWKQQTGDNVVIRQS
HGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWIKRLPDNSAPYTSTIVFLV
RKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAWGYALHHNNNDQAKAQDFVRA
LYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLAANELGKDKFEIVTPSESILAEP
TVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAKNYYRPRDAEVAKKYENAFPKLKLF
TIDEEFGGWTKAQKEHFANGGTFDQISKR