Protein Info for b3684 in Escherichia coli BW25113

Name: yidP
Annotation: predicted DNA-binding transcriptional regulator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 PF00392: GntR" amino acids 3 to 64 (62 residues), 74.1 bits, see alignment E=1.1e-24 PF08220: HTH_DeoR" amino acids 29 to 61 (33 residues), 24 bits, see alignment 5.3e-09 PF08279: HTH_11" amino acids 29 to 56 (28 residues), 24.7 bits, see alignment (E = 3.6e-09) PF07702: UTRA" amino acids 87 to 224 (138 residues), 106.5 bits, see alignment E=2e-34

Best Hits

Swiss-Prot: 100% identical to YIDP_ECOLI: Uncharacterized HTH-type transcriptional regulator YidP (yidP) from Escherichia coli (strain K12)

KEGG orthology group: K03482, GntR family transcriptional regulator, glv operon transcriptional regulator (inferred from 100% identity to eco:b3684)

Predicted SEED Role

"HTH-type transcriptional regulator YidP"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P31453 at UniProt or InterPro

Protein Sequence (238 amino acids)

>b3684 predicted DNA-binding transcriptional regulator (NCBI) (Escherichia coli BW25113)
MIYKSIAERLRIRLNSADFTLNSLLPGEKKLAEEFAVSRMTIRKAIDLLVAWGLVVRRHG
SGTYLVRKDVLHQTASLTGLVEVLKRQGKTVTSQVLIFEIMPAPPAIASQLRIQINEQIY
FSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEYIEQECGILIGGNYESLTPVL
ADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMFRNASEYQVEYHLRRLHPEKS