Protein Info for b3663 in Escherichia coli BW25113

Name: yicN
Annotation: orf, hypothetical protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF06711: DUF1198" amino acids 1 to 142 (142 residues), 243.8 bits, see alignment E=2.7e-77

Best Hits

Swiss-Prot: 100% identical to YICN_ECOL6: Uncharacterized protein YicN (yicN) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 100% identity to eco:b3663)

Predicted SEED Role

"probable membrane protein YPO2654"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0ADL3 at UniProt or InterPro

Protein Sequence (150 amino acids)

>b3663 orf, hypothetical protein (VIMSS) (Escherichia coli BW25113)
MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVESMVDQMGKSAGDEFLRY
LHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKARLAAPITDAQVRLALGFLR
ETEPEMQDINAFQMRYNAFFQPAEGVHWLH