Protein Info for b3533 in Escherichia coli BW25113

Name: yhjO
Annotation: putative cellulose synthase (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 872 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 31 to 50 (20 residues), see Phobius details amino acids 147 to 167 (21 residues), see Phobius details amino acids 173 to 190 (18 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 228 to 252 (25 residues), see Phobius details amino acids 523 to 548 (26 residues), see Phobius details amino acids 553 to 572 (20 residues), see Phobius details amino acids 639 to 659 (21 residues), see Phobius details amino acids 665 to 690 (26 residues), see Phobius details amino acids 837 to 849 (13 residues), see Phobius details TIGR03030: cellulose synthase catalytic subunit (UDP-forming)" amino acids 147 to 830 (684 residues), 1030.9 bits, see alignment E=0 PF13641: Glyco_tranf_2_3" amino acids 274 to 500 (227 residues), 60.2 bits, see alignment E=8.2e-20 PF00535: Glycos_transf_2" amino acids 277 to 447 (171 residues), 91.4 bits, see alignment E=1.9e-29 PF13506: Glyco_transf_21" amino acids 335 to 499 (165 residues), 29.2 bits, see alignment E=1.9e-10 PF13632: Glyco_trans_2_3" amino acids 356 to 563 (208 residues), 67.6 bits, see alignment E=4.4e-22 PF03552: Cellulose_synt" amino acids 446 to 664 (219 residues), 47.4 bits, see alignment E=3.5e-16 PF07238: PilZ" amino acids 694 to 790 (97 residues), 54.4 bits, see alignment E=4.3e-18

Best Hits

Swiss-Prot: 100% identical to BCSA_ECOLI: Cellulose synthase catalytic subunit [UDP-forming] (bcsA) from Escherichia coli (strain K12)

KEGG orthology group: K00694, cellulose synthase (UDP-forming) [EC: 2.4.1.12] (inferred from 100% identity to eok:G2583_4269)

MetaCyc: 100% identical to cellulose synthase catalytic subunit (Escherichia coli K-12 substr. MG1655)
Cellulose synthase (UDP-forming). [EC: 2.4.1.12]

Predicted SEED Role

"Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P37653 at UniProt or InterPro

Protein Sequence (872 amino acids)

>b3533 putative cellulose synthase (VIMSS) (Escherichia coli BW25113)
MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILAWIFIPLEHPRWQRIRA
EHKNLYPHINASRPRPLDPVRYLIQTCWLLIGASRKETPKPRRRAFSGLQNIRGRYHQWM
NELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSLILALICVTQPFNPLAQFIFL
MLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAE
TYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVDIFVPTYNEDLNVVKNTIYASLGID
WPKDKLNIWILDDGGREEFRQFAQNVGVKYIARTTHEHAKAGNINNALKYAKGEFVSIFD
CDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHFFSPDPFERNLGRFRKTPNEGTLFYGLVQ
DGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQAA
GLATESLSAHIGQRIRWARGMVQIFRLDNPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIF
LTAPLAFLLLHAYIIYAPALMIALFVLPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWY
IAPPTLVALINPHKGKFNVTAKGGLVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYG
PPTEMLTVVVSMVWVFYNLIVLGGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCT
VQDFSDGGLGIKINGQAQILEGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQ
QHIDFVQCTFARADTWALWQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRV
LTSLVSWVVSFIPRRPERSETAQPSDQALAQQ