Protein Info for b3495 in Escherichia coli BW25113

Name: uspA
Annotation: universal stress global response regulator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 PF00582: Usp" amino acids 3 to 138 (136 residues), 84.6 bits, see alignment E=4.9e-28

Best Hits

Swiss-Prot: 100% identical to USPA_SHIFL: Universal stress protein A (uspA) from Shigella flexneri

KEGG orthology group: K06149, universal stress protein A (inferred from 100% identity to eco:b3495)

Predicted SEED Role

"Universal stress protein A" in subsystem Universal stress protein family

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AED0 at UniProt or InterPro

Protein Sequence (144 amino acids)

>b3495 universal stress global response regulator (NCBI) (Escherichia coli BW25113)
MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQK
RISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKYDMDLVVCGHHQDFWSKLM
SSARQLINTVHVDMLIVPLRDEEE