Protein Info for b3434 in Escherichia coli BW25113

Name: yhgN
Annotation: predicted antibiotic transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 signal peptide" amino acids 1 to 6 (6 residues), see Phobius details transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 42 to 65 (24 residues), see Phobius details amino acids 71 to 93 (23 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 138 to 162 (25 residues), see Phobius details amino acids 174 to 194 (21 residues), see Phobius details PF01914: MarC" amino acids 1 to 195 (195 residues), 222.2 bits, see alignment E=2.4e-70 TIGR00427: membrane protein, MarC family" amino acids 4 to 191 (188 residues), 106.1 bits, see alignment E=9.9e-35

Best Hits

Swiss-Prot: 100% identical to YHGN_ECOLI: UPF0056 inner membrane protein YhgN (yhgN) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b3434)

Predicted SEED Role

"Multiple antibiotic resistance protein marC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P67143 at UniProt or InterPro

Protein Sequence (197 amino acids)

>b3434 predicted antibiotic transporter (NCBI) (Escherichia coli BW25113)
MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEK
ILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTI
LATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFLRLLGEKGVNALERLMGLILV
MMATQMFLDGIRMWMKG