Protein Info for b2948 in Escherichia coli BW25113

Name: yqgE
Annotation: orf, hypothetical protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 PF02622: DUF179" amino acids 12 to 174 (163 residues), 178.1 bits, see alignment E=6.5e-57

Best Hits

Swiss-Prot: 100% identical to YQGE_SHIDS: UPF0301 protein YqgE (yqgE) from Shigella dysenteriae serotype 1 (strain Sd197)

KEGG orthology group: K07735, putative transcriptional regulator (inferred from 100% identity to eco:b2948)

Predicted SEED Role

"UPF0301 protein YqgE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0A8W5 at UniProt or InterPro

Protein Sequence (187 amino acids)

>b2948 orf, hypothetical protein (VIMSS) (Escherichia coli BW25113)
MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPE
PRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQ
PSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTM
PGVAGHA