Protein Info for b2645 in Escherichia coli BW25113

Name: yfjZ
Annotation: CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 105 PF06154: CbeA_antitoxin" amino acids 5 to 104 (100 residues), 175.9 bits, see alignment E=1.2e-56

Best Hits

Swiss-Prot: 100% identical to YFJZ_ECOLI: Antitoxin YfjZ (yfjZ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2645)

Predicted SEED Role

"YfjZ protein (antitoxin to YpjF)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P52141 at UniProt or InterPro

Protein Sequence (105 amino acids)

>b2645 CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) (Escherichia coli BW25113)
MSNTTWGLQRDITPRLGARLVQEGNQLHYLADRASITGKFSDAECPKLDVVFPHFISQIE
SMLTTGELNPRHAQCVTLYHNGFTCEADTLGSCGYVYIAVYPTQR