Protein Info for b2624 in Escherichia coli BW25113

Name: alpA
Annotation: CP4-57 prophage; DNA-binding transcriptional activator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 70 PF05930: Phage_AlpA" amino acids 8 to 63 (56 residues), 79 bits, see alignment E=9.3e-27

Best Hits

Swiss-Prot: 100% identical to ALPA_ECOLI: DNA-binding transcriptional activator AlpA (alpA) from Escherichia coli (strain K12)

KEGG orthology group: K07733, prophage regulatory protein (inferred from 100% identity to eco:b2624)

Predicted SEED Role

"Prophage CP4-57 regulatory protein alpA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P33997 at UniProt or InterPro

Protein Sequence (70 amino acids)

>b2624 CP4-57 prophage; DNA-binding transcriptional activator (NCBI) (Escherichia coli BW25113)
MNNRSAVRILRLPAVIQKTGMARATIYDWLNPKSPRYDATFPKKRMLGVKSVGWIEAEID
EWLSQRCKLI