Protein Info for b2433 in Escherichia coli BW25113

Name: b2433
Annotation: orf, hypothetical protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 61 to 78 (18 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details PF11143: DUF2919" amino acids 6 to 145 (140 residues), 164.6 bits, see alignment E=9.8e-53

Best Hits

Swiss-Prot: 100% identical to YFEZ_ECOLI: Inner membrane protein YfeZ (yfeZ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2433)

Predicted SEED Role

"Inner membrane protein YfeZ"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P76538 at UniProt or InterPro

Protein Sequence (149 amino acids)

>b2433 orf, hypothetical protein (VIMSS) (Escherichia coli BW25113)
MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASREQGTALLNLFYPDHDN
FWLGLIPGIPAVLAFLLSGRRATFPRTWRVLYFLLLLAQVVLLCWQPWLWLNGESVSGIG
LALVVADIVALIWLLTNRRLRACFYEVKE