Protein Info for b2305 in Escherichia coli BW25113

Name: yfcI
Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 PF04754: Transposase_31" amino acids 8 to 209 (202 residues), 307.5 bits, see alignment E=2e-96 TIGR01784: conserved hypothetical protein" amino acids 9 to 291 (283 residues), 186.6 bits, see alignment E=4e-59

Best Hits

Swiss-Prot: 100% identical to RPNB_ECOLI: Recombination-promoting nuclease RpnB (rpnB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2305)

MetaCyc: 66% identical to recombination-promoting nuclease RpnA (Escherichia coli K-12 substr. MG1655)
RXN0-7100

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P77768 at UniProt or InterPro

Protein Sequence (296 amino acids)

>b2305 hypothetical protein (NCBI) (Escherichia coli BW25113)
MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLPAPLRKLCDLTTLKLEPNSFIDEDLRQY
YSDLLWSVKTQEGVGYIYVVIEHQSKPEELMAFRMMRYSIAAMQNHLDAGYKELPLVLPM
LFYHGCRSPYPYSLCWLDEFAEPAIARKIYSSAFPLVDITVVPDDEIMQHRKMALLELIQ
KHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQTGDAQRFRAFIGEIAERAPQEK
EKLMTIADRLREEGAMQGKHEEALRIAQEMLDRGLDRELVMMVTRLSPDDLIAQSH