Protein Info for b2135 in Escherichia coli BW25113

Name: yohC
Annotation: orf, hypothetical protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 195 transmembrane" amino acids 33 to 53 (21 residues), see Phobius details amino acids 65 to 91 (27 residues), see Phobius details amino acids 103 to 122 (20 residues), see Phobius details amino acids 128 to 149 (22 residues), see Phobius details amino acids 169 to 190 (22 residues), see Phobius details PF04893: Yip1" amino acids 5 to 178 (174 residues), 119.2 bits, see alignment E=9.2e-39

Best Hits

Swiss-Prot: 100% identical to YOHC_ECOL6: Inner membrane protein YohC (yohC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 100% identity to eco:b2135)

Predicted SEED Role

"Putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AD17 at UniProt or InterPro

Protein Sequence (195 amino acids)

>b2135 orf, hypothetical protein (VIMSS) (Escherichia coli BW25113)
MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICAFIGTTQIGWNFGDGTI
LKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPSLAHCMVFAGYVATPLFLS
GLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKEEGLSFSSSTLAIGVLVLEVL
LALTVILWGYGYRLF