Protein Info for b2015 in Escherichia coli BW25113

Name: yeeY
Annotation: putative transcriptional regulator LYSR-type (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF00126: HTH_1" amino acids 6 to 63 (58 residues), 50 bits, see alignment E=2.3e-17 PF03466: LysR_substrate" amino acids 89 to 291 (203 residues), 94.8 bits, see alignment E=5e-31

Best Hits

Swiss-Prot: 100% identical to YEEY_ECOLI: Uncharacterized HTH-type transcriptional regulator YeeY (yeeY) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2015)

Predicted SEED Role

"Hypothetical transcriptional regulator yeeY"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P76369 at UniProt or InterPro

Protein Sequence (309 amino acids)

>b2015 putative transcriptional regulator LYSR-type (VIMSS) (Escherichia coli BW25113)
MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESDLNIQLLDRSGHRAKFT
RTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDTFPFSLLAPLIEAFYQHHS
VTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFGFSRLGDLEQVFAVAPHHPLA
LEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQEAITVFDFKTKLELQISGLGCGY
LPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQTAGLASGWWRDEILANSAIAGVYA
KSDDGKSAI