Protein Info for b1945 in Escherichia coli BW25113

Name: fliM
Annotation: flagellar motor switch protein M (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 TIGR01397: flagellar motor switch protein FliM" amino acids 4 to 321 (318 residues), 399.2 bits, see alignment E=6.5e-124 PF02154: FliM" amino acids 38 to 231 (194 residues), 267 bits, see alignment E=1.1e-83 PF01052: FliMN_C" amino acids 253 to 321 (69 residues), 58 bits, see alignment E=7.4e-20

Best Hits

Swiss-Prot: 100% identical to FLIM_ECOLI: Flagellar motor switch protein FliM (fliM) from Escherichia coli (strain K12)

KEGG orthology group: K02416, flagellar motor switch protein FliM (inferred from 100% identity to eco:b1945)

Predicted SEED Role

"Flagellar motor switch protein FliM" in subsystem Bacterial Chemotaxis or Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P06974 at UniProt or InterPro

Protein Sequence (334 amino acids)

>b1945 flagellar motor switch protein M (NCBI) (Escherichia coli BW25113)
MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQRRVVRERLQALEIINER
FARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSP
SLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYV
RSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENSR
NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLNPGDVLPIEKPDRIIAHVDGVP
VLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK