Protein Info for b1917 in Escherichia coli BW25113

Name: yecC
Annotation: predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00005: ABC_tran
  • amino acids 19 to 173 (155 residues), 135.8 bits, E=3.3e-43

Best Hits

Swiss-Prot: 100% identical to YECC_ECOLI: L-cystine transport system ATP-binding protein YecC (yecC) from Escherichia coli (strain K12)

KEGG orthology group: K10010, cystine transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 100% identity to eco:b1917)

MetaCyc: 100% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Cystine ABC transporter, ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 7.4.2.12

Sequence Analysis Tools

See P37774 at UniProt or InterPro

Protein Sequence (250 amino acids)

>b1917 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) (Escherichia coli BW25113)
MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRSINLLEQPEAGTI
TVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEE
ATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELV
GEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGAAKALFADPEQPRT
RQFLEKFLLQ