Protein Info for b1882 in Escherichia coli BW25113

Name: cheY
Annotation: chemotaxis regulator transmitting signal to flagellar motor component (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 129 PF00072: Response_reg" amino acids 9 to 120 (112 residues), 109.7 bits, see alignment E=4.4e-36

Best Hits

Swiss-Prot: 100% identical to CHEY_ECOLI: Chemotaxis protein CheY (cheY) from Escherichia coli (strain K12)

KEGG orthology group: K03413, two-component system, chemotaxis family, response regulator CheY (inferred from 100% identity to eco:b1882)

Predicted SEED Role

"Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AE67 at UniProt or InterPro

Protein Sequence (129 amino acids)

>b1882 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) (Escherichia coli BW25113)
MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNM
PNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKL
NKIFEKLGM