Protein Info for b1878 in Escherichia coli BW25113

Name: flhE
Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 130 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF06366: FlhE" amino acids 28 to 130 (103 residues), 140.5 bits, see alignment E=1e-45

Best Hits

Swiss-Prot: 100% identical to FLHE_ECOLI: Flagellar protein FlhE (flhE) from Escherichia coli (strain K12)

KEGG orthology group: K03516, flagellar protein FlhE (inferred from 100% identity to eco:b1878)

Predicted SEED Role

"Flagellar protein FlhE" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P76297 at UniProt or InterPro

Protein Sequence (130 amino acids)

>b1878 hypothetical protein (NCBI) (Escherichia coli BW25113)
MRTLLAILLFPLLVQAAGEGMWQASSVGITLNHRGESMSSAPLSTRQPASGLMTLVAWRY
QLIGPTPSGLRVRLCSQSRCVELEGQSGTTVAFSGIAAAEPLRFIWEVPGGGRLIPPLKV
QRNEVIVNYR