Protein Info for b1659 in Escherichia coli BW25113

Name: ydhB
Annotation: predicted DNA-binding transcriptional regulator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 PF00126: HTH_1" amino acids 7 to 62 (56 residues), 74.2 bits, see alignment E=6.4e-25 PF03466: LysR_substrate" amino acids 88 to 290 (203 residues), 100.4 bits, see alignment E=9.7e-33

Best Hits

Swiss-Prot: 100% identical to YDHB_ECO57: Uncharacterized HTH-type transcriptional regulator YdhB (ydhB) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 100% identity to eco:b1659)

Predicted SEED Role

"LysR-family transcriptional regulator YdhB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0ACR2 at UniProt or InterPro

Protein Sequence (310 amino acids)

>b1659 predicted DNA-binding transcriptional regulator (NCBI) (Escherichia coli BW25113)
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTA
AGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDD
VELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLAL
MDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMV
PTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLR
EPEETPATGD