Protein Info for b1540 in Escherichia coli BW25113

Name: ydfH
Annotation: predicted DNA-binding transcriptional regulator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 PF00392: GntR" amino acids 15 to 75 (61 residues), 61.9 bits, see alignment E=3.6e-21 PF07729: FCD" amino acids 89 to 208 (120 residues), 98.1 bits, see alignment E=5.4e-32

Best Hits

Swiss-Prot: 100% identical to YDFH_SHIFL: Uncharacterized HTH-type transcriptional regulator YdfH (ydfH) from Shigella flexneri

KEGG orthology group: None (inferred from 100% identity to eco:b1540)

Predicted SEED Role

"Transcriptional regulator, GntR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0ACM2 at UniProt or InterPro

Protein Sequence (228 amino acids)

>b1540 predicted DNA-binding transcriptional regulator (NCBI) (Escherichia coli BW25113)
MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVRFNVSRQPVREAFIKLA
ENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAASMITESQCYQLEQNLHQQ
RIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLKATVDRVRYMSFDHVSPPEML
LRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIRQENSDWFSEE