Protein Info for b1430 in Escherichia coli BW25113

Name: tehB
Annotation: predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 TIGR00477: tellurite resistance protein TehB" amino acids 1 to 196 (196 residues), 378.4 bits, see alignment E=5.7e-118 PF03848: TehB" amino acids 1 to 193 (193 residues), 368.2 bits, see alignment E=2.6e-114 PF05175: MTS" amino acids 23 to 102 (80 residues), 32.7 bits, see alignment E=2e-11 PF13489: Methyltransf_23" amino acids 29 to 133 (105 residues), 40.1 bits, see alignment E=1.1e-13 PF13847: Methyltransf_31" amino acids 32 to 133 (102 residues), 36 bits, see alignment E=2.1e-12 PF08241: Methyltransf_11" amino acids 35 to 130 (96 residues), 48.3 bits, see alignment E=4.7e-16 PF13649: Methyltransf_25" amino acids 35 to 128 (94 residues), 52.8 bits, see alignment E=1.8e-17 PF08242: Methyltransf_12" amino acids 35 to 128 (94 residues), 41.9 bits, see alignment E=4.9e-14

Best Hits

Swiss-Prot: 100% identical to TEHB_ECOLI: Tellurite methyltransferase (tehB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b1430)

MetaCyc: 100% identical to tellurite methyltransferase (Escherichia coli K-12 substr. MG1655)
RXN0-6576 [EC: 2.1.1.265]

Predicted SEED Role

"Tellurite resistance protein TehB"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.265

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P25397 at UniProt or InterPro

Protein Sequence (197 amino acids)

>b1430 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) (Escherichia coli BW25113)
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDK
NAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILSTVVLMFLEAKTIPGLIANM
QRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYYEGWERVKYNEDVGELHRTDA
NGNRIKLRFATMLARKK