Protein Info for b1389 in Escherichia coli BW25113

Name: paaB
Annotation: predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02157: phenylacetate-CoA oxygenase, PaaH subunit
  • amino acids 6 to 95 (90 residues), 166.9 bits, E=4.4e-54
• PF06243: PaaB
  • amino acids 6 to 91 (86 residues), 147.3 bits, E=6.4e-48

Best Hits

Swiss-Prot: 100% identical to PAAB_ECOLI: 1,2-phenylacetyl-CoA epoxidase, subunit B (paaB) from Escherichia coli (strain K12)

KEGG orthology group: K02610, phenylacetic acid degradation protein (inferred from 100% identity to eco:b1389)

MetaCyc: 100% identical to phenylacetyl-CoA 1,2-epoxidase subunit B (Escherichia coli K-12 substr. MG1655)
RXN0-2042 [EC: 1.14.13.149]

Predicted SEED Role

"Phenylacetate-CoA oxygenase, PaaH subunit"

MetaCyc Pathways

• superpathway of phenylethylamine degradation (11/11 steps found)
• phenylacetate degradation I (aerobic) (9/9 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.149

Sequence Analysis Tools

See P76078 at UniProt or InterPro

Protein Sequence (95 amino acids)

>b1389 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) (Escherichia coli BW25113)
MSNVYWPLYEVFVRGKQGLSHRHVGSLHAADERMALENARDAYTRRSEGCSIWVVKASEI
VASQPEERGEFFDPAESKVYRHPTFYTIPDGIEHM