Protein Info for b1372 in Escherichia coli BW25113

Name: b1372
Annotation: putative membrane protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1120 PF08400: phage_tail_N" amino acids 1 to 134 (134 residues), 239.7 bits, see alignment E=1.6e-75 PF21446: Gp34_C" amino acids 663 to 762 (100 residues), 95.7 bits, see alignment E=5.4e-31 PF07484: Collar" amino acids 907 to 954 (48 residues), 43.2 bits, see alignment (E = 6.2e-15) PF03335: Phage_fiber" amino acids 970 to 983 (14 residues), 11.3 bits, see alignment (E = 6.8e-05) amino acids 1002 to 1015 (14 residues), 14.1 bits, see alignment (E = 8.7e-06) amino acids 1016 to 1025 (10 residues), 9.1 bits, see alignment (E = 0.00037) amino acids 1055 to 1068 (14 residues), 12.1 bits, see alignment (E = 3.8e-05) amino acids 1070 to 1081 (12 residues), 9.7 bits, see alignment (E = 0.00022) amino acids 1079 to 1090 (12 residues), 9.1 bits, see alignment (E = 0.00035)

Best Hits

Swiss-Prot: 96% identical to STFR_ECOLI: Prophage side tail fiber protein homolog StfR (stfR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to ebw:BWG_1200)

Predicted SEED Role

"Phage tail fiber protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P76072 at UniProt or InterPro

Protein Sequence (1120 amino acids)

>b1372 putative membrane protein (VIMSS) (Escherichia coli BW25113)
MAVKISGVLKDGTGKPVQNCTIQLKAKRNSTTVVVNTLASENPDEAGRYSMDVEYGQYSV
ILLVEGFPPSHAGTITVYEDSQPGTLNDFLGAMTEDDARPEALRRFELMVEEVARNASAV
AQNTAAAKKSASDASTSAREAATHAADAADSARAASTSAGQAASSAQSASSSAGTASTKA
TEASKSAAAAESSKSAAATSAGAAKTSETNASASLQSAATSASTATTKASEAATSARDAA
ASKEAAKSSETNASSSASSAASSATAAGNSAKAAKTSETNARSSETAAGQSASAAAGSKT
AAASSASAASTSAGQASASATAAGKSAESAASSASTATTKAGEATEQASAAARSASAAKT
SETNAKASETSAESSKTAAASSASSAASSASSASASKDEATRQASAAKSSATTASTKATE
AAGSATAAAQSKSTAESAATRAETAAKRAEDIASAVALEDASTTKKGIVQLSSATNSTSE
TLAATPKAVKSAYDNAEKRLQKDQNGADIPDKGCFLNNINAVSKTDFADKRGMRYVRVNA
PAGATSGKYYPVVVMRSAGSVSELASRVIITTATRTAGDPMNNCEFNGFVMPGGWTDRGR
YAYGMFWQYQNNERAIHSIMMSNKGDDLRSVFYVDGAAFPVFAFIEDGLSISAPGADLVV
NDTTYKFGATNPATECIAADVILDFKSGRGFYESHSLIVNDNLSCKKLFATDEIVARGGN
QIRMIGGEYGALWRNDGAKTYLLLTNQGDVYGGWNTLRPFAIDNATGELVIGTKLSASLN
GNALTATKLQTPRRVSGVEFDGSKDITLTAAHVAAFARRATDTYADADGGVPWNAESGAY
NVTRSGDSYILVNFYTGVGSCRTLQMKAHYRNGGLFYRSSRDGYGFEEDWAEVYTSKNLP
PESYPVGAPIPWPSDTVPSGYALMQGQAFDKSAYPKLAAAYPSGVIPDMRGWTIKGKPAS
GRAVLSQEQDGIKSHTHSASASSTDLGTKTTSSFDYGTKSTNNTGAHTHSVSGSTNSAGA
HTHSLANVNTASANSGAGSASTRLSVVHNQNYATSSAGAHTHSLSGTAASAGAHAHTVGI
GAHTHSVAIGSHGHTITVNAAGNAENTVKNIAFNYIVRLA