Protein Info for b1214 in Escherichia coli BW25113

Name: ychA
Annotation: predicted transcriptional regulator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 PF13369: Transglut_core2" amino acids 33 to 184 (152 residues), 149 bits, see alignment E=7.9e-48 PF13371: TPR_9" amino acids 187 to 259 (73 residues), 87.6 bits, see alignment E=4.3e-29

Best Hits

Swiss-Prot: 100% identical to SIRB1_ECOLI: UPF0162 protein YchA (ychA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b1214)

Predicted SEED Role

"FIG002708: Protein SirB1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AGM5 at UniProt or InterPro

Protein Sequence (269 amino acids)

>b1214 predicted transcriptional regulator (NCBI) (Escherichia coli BW25113)
MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSLAKEEISQLLPLEEQLE
KLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLGAVLLWVANRLDLPLLPVI
FPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNISPSAELFYEDLDEADNIEVI
RKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEIRDRGLIYAQLDCEHVALNDLSY
FVEQCPEDPISEMIRAQINNIAHKHIVLH