Protein Info for b1188 in Escherichia coli BW25113

Name: ycgB
Updated annotation (from data): ycgB component of nitrogen-related signalling system (of yeaGH-ycgB)
Rationale: conserved cofitness; yeaG is a protein kinase
Original annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 PF04293: SpoVR" amino acids 19 to 450 (432 residues), 615.8 bits, see alignment E=1.8e-189

Best Hits

Swiss-Prot: 100% identical to YCGB_ECOLI: Uncharacterized protein YcgB (ycgB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b1188)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P29013 at UniProt or InterPro

Protein Sequence (510 amino acids)

>b1188 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (Escherichia coli BW25113)
MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTYPHQIEVITSEQMMDAY
SSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNPCIAYLMEENTITMQALVM
AHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITECEERYGVDEVERLLDSCHALM
NYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWRTLPKREEEKTVAEARRYPSEPQ
ENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQKQTQVMNEGWATFWHYTILNHLYDE
GKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINPYALGFAMFQDIKRICQSPTEEDKYWF
PDIAGSDWLETLHFAMRDFKDESFISQFLSPKVMRDFRFFTVLDDDRHNYLEISAIHNEE
GYREIRNRLSSQYNLSNLEPNIQIWNVDLRGDRSLTLRYIPHNRAPLDRGRKEVLKHVHR
LWGFDVMLEQQNEDGSIELLERCPPRMGNL