Protein Info for b1140 in Escherichia coli BW25113

Name: intE
Annotation: e14 prophage; predicted integrase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 PF09003: Arm-DNA-bind_1" amino acids 1 to 73 (73 residues), 127.2 bits, see alignment E=2e-41 PF00589: Phage_integrase" amino acids 193 to 364 (172 residues), 61.3 bits, see alignment E=1.1e-20

Best Hits

Swiss-Prot: 100% identical to INTE_ECOLI: Prophage integrase IntE (intE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b1140)

Predicted SEED Role

"Prophage lambda integrase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P75969 at UniProt or InterPro

Protein Sequence (375 amino acids)

>b1140 e14 prophage; predicted integrase (NCBI) (Escherichia coli BW25113)
MAARPRKNNVSVPNLYPLYSRKVNKVYWRYKHPVTGKFHALGTNEAEAIAIATEANTRLA
EQRTRQILAISDRIATSKGKAITTSTWLDRYQAIQDDRLKSGDIRLNTYKQKAKPVSLLR
ERAGMKLISAVDVRDIAQLLDEYIAAGRPRMAQVVRSVLIDVFKEAQHYGEVPPGYNPAL
ATKQPRRKITRQRLSLEEWKKIFDIADATHRYMGNAMLLALVTGQRLGDISRMKFSDIWD
DHLHVIQEKTGSKIAIPLSLRLNAINWSLRDVVARCRDYAVSAYLVHFFRSTSQAERGAQ
VKANTLTMNFSKARDLARIDWGEGSPATFHEQRSLSERLYKEQGLDTQKLLGHKTQQQTD
RYHDDRGKGWSKVAL