Protein Info for b1137 in Escherichia coli BW25113

Name: ymfD
Annotation: e14 prophage; predicted SAM-dependent methyltransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 PF03848: TehB" amino acids 37 to 153 (117 residues), 21.9 bits, see alignment E=1.6e-08 PF08241: Methyltransf_11" amino acids 44 to 148 (105 residues), 21.5 bits, see alignment E=4.6e-08 PF08242: Methyltransf_12" amino acids 44 to 145 (102 residues), 32.2 bits, see alignment E=2.3e-11

Best Hits

Swiss-Prot: 100% identical to YMFD_ECOLI: Uncharacterized protein YmfD (ymfD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b1137)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P75967 at UniProt or InterPro

Protein Sequence (221 amino acids)

>b1137 e14 prophage; predicted SAM-dependent methyltransferase (NCBI) (Escherichia coli BW25113)
MVLALNYNMHGVNIRSENAAKPHTMPSRYLCEYIRSIEKNGHALDFGCGKLRYSDELISK
FDEVTFLDSKRQLEREQIIRGIKTKIIDYVPRYYKNANTVAFEDVDKIIGGYDFILCSNV
LSAVPCRDTIDKIVLSIKRLLKSGGETLIVNQYKSSYFKKYETGRKHLYGYIYKNSKSVS
YYGLLDELAVQEICSSHGLEILKSWSKAGSSYVTVGSCNAI