Protein Info for b1113 in Escherichia coli BW25113

Name: ycfS
Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF01476: LysM" amino acids 48 to 91 (44 residues), 24.8 bits, see alignment 2.6e-09 PF03734: YkuD" amino acids 103 to 240 (138 residues), 80.2 bits, see alignment E=3.8e-26 PF17969: Ldt_C" amino acids 244 to 310 (67 residues), 85.7 bits, see alignment E=4.3e-28

Best Hits

Swiss-Prot: 100% identical to YCFS_ECOLI: Probable L,D-transpeptidase YcfS (ycfS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b1113)

MetaCyc: 100% identical to L,D-transpeptidase LdtC (Escherichia coli K-12 substr. MG1655)
RXN0-5401

Predicted SEED Role

"L,D-transpeptidase YcfS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P75954 at UniProt or InterPro

Protein Sequence (320 amino acids)

>b1113 hypothetical protein (NCBI) (Escherichia coli BW25113)
MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPPAGSRLVGENKFHVVENDGGSLEAIA
KKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPREGIVINIAELRLYYYPPGK
NSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTANIRARYKAQGIELPAVVPAGL
DNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCIRLRDDDIKTLFSQVTPGTKVNI
INTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPITLNSAMQSFKDAAQTDAEVMQHVM
DVRSGMPVDVRRHQVSPQTL