Protein Info for b0996 in Escherichia coli BW25113

Name: torC
Annotation: trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details TIGR02162: trimethylamine-N-oxide reductase c-type cytochrome TorC" amino acids 2 to 383 (382 residues), 659.7 bits, see alignment E=8.4e-203 PF03264: Cytochrom_NNT" amino acids 11 to 184 (174 residues), 237.8 bits, see alignment E=9.5e-75

Best Hits

Swiss-Prot: 100% identical to TORC_ECOLI: Cytochrome c-type protein TorC (torC) from Escherichia coli (strain K12)

KEGG orthology group: K03532, trimethylamine-N-oxide reductase (cytochrome c) 1, cytochrome c-type subunit TorC (inferred from 100% identity to eco:b0996)

MetaCyc: 100% identical to cytochrome c menaquinol dehydrogenase TorC (Escherichia coli K-12 substr. MG1655)
RXN0-5264

Predicted SEED Role

"Cytochrome c-type protein TorC" in subsystem trimethylamine N-oxide (TMAO) reductase

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P33226 at UniProt or InterPro

Protein Sequence (390 amino acids)

>b0996 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit (NCBI) (Escherichia coli BW25113)
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEE
YKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRA
ELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQ
LPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDG
DWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQ
ATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLD
KREERTLLKYLQMNASDTAGKAHGDKKEEK