Protein Info for b0994 in Escherichia coli BW25113

Name: torT
Annotation: periplasmic sensory protein associated with the TorRS two-component regulatory system (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00532: Peripla_BP_1" amino acids 44 to 337 (294 residues), 292.9 bits, see alignment E=2.8e-91 TIGR02955: TMAO reductase system periplasmic protein TorT" amino acids 46 to 334 (289 residues), 437.5 bits, see alignment E=1.2e-135 PF13407: Peripla_BP_4" amino acids 52 to 296 (245 residues), 80 bits, see alignment E=2.2e-26

Best Hits

Swiss-Prot: 100% identical to TORT_ECOLI: Periplasmic protein TorT (torT) from Escherichia coli (strain K12)

KEGG orthology group: K11930, periplasmic protein TorT (inferred from 100% identity to eco:b0994)

Predicted SEED Role

"Periplasmic protein torT precursor" in subsystem trimethylamine N-oxide (TMAO) reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P38683 at UniProt or InterPro

Protein Sequence (342 amino acids)

>b0994 periplasmic sensory protein associated with the TorRS two-component regulatory system (NCBI) (Escherichia coli BW25113)
MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRAWKLCALYPSLKDSYWL
SLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWGAEAILLGSSTTSFPDLQK
QVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQWAHGKPLNVLLMPGPDNAGG
SKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQEMLERHPEIDVVAGTAIAAEAAM
GEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASDQMVWQGELAVEQAIRQLQGQSVSD
NVSPPILVLTPKNADREHIRRSLSPGGFRPVYFYQHTSAAKK