Protein Info for b0712 in Escherichia coli BW25113
Name: ybgK
Annotation: predicted enzyme subunit (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to PXPC_ECOLI: 5-oxoprolinase subunit C (pxpC) from Escherichia coli (strain K12)
KEGG orthology group: None (inferred from 100% identity to eco:b0712)MetaCyc: 100% identical to 5-oxoprolinase component C (Escherichia coli K-12 substr. MG1655)
5-oxoprolinase (ATP-hydrolyzing). [EC: 3.5.2.9]
Predicted SEED Role
"Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54)" (EC 3.5.1.54)
MetaCyc Pathways
- allantoin degradation IV (anaerobic) (8/9 steps found)
- uracil degradation III (5/5 steps found)
- L-citrulline degradation (3/3 steps found)
- cyanate degradation (3/3 steps found)
- γ-glutamyl cycle (5/6 steps found)
- 5-oxo-L-proline metabolism (5/6 steps found)
- L-arginine degradation V (arginine deiminase pathway) (3/4 steps found)
- urea degradation I (2/3 steps found)
- superpathway of allantoin degradation in yeast (4/6 steps found)
- cyanuric acid degradation II (3/5 steps found)
- cyanuric acid degradation I (2/5 steps found)
- superpathway of atrazine degradation (3/8 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- Atrazine degradation
- Glutathione metabolism
- Urea cycle and metabolism of amino groups
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.54
Use Curated BLAST to search for 3.5.1.54 or 3.5.2.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See P75745 at UniProt or InterPro
Protein Sequence (310 amino acids)
>b0712 predicted enzyme subunit (NCBI) (Escherichia coli BW25113) MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLVGNDANAPALEITLGQL TVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTLKRPQHGMRSYLAVAGGID VPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKSKRDSMEAQGVKQLLWGNRIRALPGP EYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKRTTDRELLSHGLLPGVVQVPHNG QPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQPIHFVQCSLEEALKARQDQQRYFE QLAWRLHNEN