Protein Info for b0660 in Escherichia coli BW25113

Name: ybeZ
Annotation: predicted protein with nucleoside triphosphate hydrolase domain (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 PF02562: PhoH" amino acids 118 to 321 (204 residues), 330 bits, see alignment E=7.4e-103 PF13604: AAA_30" amino acids 123 to 274 (152 residues), 32 bits, see alignment E=1.6e-11 PF13245: AAA_19" amino acids 126 to 274 (149 residues), 26.2 bits, see alignment E=1.1e-09

Best Hits

Swiss-Prot: 100% identical to PHOL_ECO57: PhoH-like protein (ybeZ) from Escherichia coli O157:H7

KEGG orthology group: K06217, phosphate starvation-inducible protein PhoH and related proteins (inferred from 100% identity to eco:b0660)

Predicted SEED Role

"Phosphate starvation-inducible protein PhoH, predicted ATPase" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0A9K3 at UniProt or InterPro

Protein Sequence (346 amino acids)

>b0660 predicted protein with nucleoside triphosphate hydrolase domain (RefSeq) (Escherichia coli BW25113)
MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRDNHFKLTGRPICVTAAA
DILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESVPEYGKAVNIKTKRGVIKP
RTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDALERQEIRRILLTRPAVEAGEK
LGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIERNVIEVAPLAYMRGRTLNDAFII
LDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDLPRNTKSGLRHAIEVLADVEEISFN
FFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAALAAERKREEQEQK