Protein Info for b0591 in Escherichia coli BW25113

Name: ybdA
Annotation: predicted transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details amino acids 53 to 75 (23 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 111 to 135 (25 residues), see Phobius details amino acids 148 to 171 (24 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 219 to 242 (24 residues), see Phobius details amino acids 257 to 276 (20 residues), see Phobius details amino acids 288 to 305 (18 residues), see Phobius details amino acids 311 to 333 (23 residues), see Phobius details amino acids 352 to 374 (23 residues), see Phobius details amino acids 380 to 399 (20 residues), see Phobius details PF05977: MFS_3" amino acids 16 to 397 (382 residues), 73.9 bits, see alignment E=9.5e-25 PF07690: MFS_1" amino acids 22 to 239 (218 residues), 66.7 bits, see alignment E=1.8e-22 amino acids 239 to 405 (167 residues), 37.5 bits, see alignment E=1.4e-13

Best Hits

Swiss-Prot: 100% identical to ENTS_ECOHS: Enterobactin exporter EntS (entS) from Escherichia coli O9:H4 (strain HS)

KEGG orthology group: K08225, MFS transporter, ENTS family, enterobactin (siderophore) exporter (inferred from 100% identity to eco:b0591)

MetaCyc: 100% identical to enterobactin exporter EntS (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-496

Predicted SEED Role

"Enterobactin exporter EntS" in subsystem Siderophore Enterobactin

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P24077 at UniProt or InterPro

Protein Sequence (416 amino acids)

>b0591 predicted transporter (NCBI) (Escherichia coli BW25113)
MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTL
TGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWD
GFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYG
LAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMAS
AVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFL
AIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGD
AIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRHFRQTPPQVTASDS