Protein Info for b0556 in Escherichia coli BW25113

Name: rzpD
Annotation: DLP12 prophage; predicted murein endopeptidase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 153 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF03245: Phage_lysis" amino acids 29 to 153 (125 residues), 174.2 bits, see alignment E=6.4e-56

Best Hits

Swiss-Prot: 100% identical to RZPD_ECOLI: Prophage Rz endopeptidase RzpD (rzpD) from Escherichia coli (strain K12)

KEGG orthology group: K14744, putative Rz endopeptidase from lambdoid prophage DLP12 [EC: 3.4.-.-] (inferred from 100% identity to eco:b0556)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.-.-

Use Curated BLAST to search for 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P75719 at UniProt or InterPro

Protein Sequence (153 amino acids)

>b0556 DLP12 prophage; predicted murein endopeptidase (NCBI) (Escherichia coli BW25113)
MSRVTAIISALIICIIVSLSWAVNHYRDNAIAYKVQRDKNARELKLANAAITDMQMRQRD
VAALDAKYTKELADAKAENDALRDDVAAGRRRLHIKAVCQSVREATTASGVDNAASPRLA
DTAERDYFTLRERLITMQKQLEGTQKYINEQCR