Protein Info for b0533 in Escherichia coli BW25113

Name: sfmH
Annotation: predicted fimbrial-like adhesin protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00419: Fimbrial" amino acids 179 to 327 (149 residues), 104.5 bits, see alignment E=3.4e-34

Best Hits

Swiss-Prot: 100% identical to SFMH_ECOLI: Uncharacterized fimbrial-like protein SfmH (sfmH) from Escherichia coli (strain K12)

KEGG orthology group: K07356, fimbrial protein (inferred from 100% identity to eco:b0533)

Predicted SEED Role

"Fimbriae-like adhesin SfmH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P75715 at UniProt or InterPro

Protein Sequence (327 amino acids)

>b0533 predicted fimbrial-like adhesin protein (RefSeq) (Escherichia coli BW25113)
MAMACLCLANISWATVCANSTGVAEDEHYDLSNIFNSTNNQPGQIVVLPEKSGWVGVSAI
CPPGTLVNYTYRSYVTNFIVQETIDNYKYMQLHDYLLGAMSLVDSVMDIQFPPQNYIRMG
TDPNVSQNLPFGVMDSRLIFRLKVIRPFINMVEIPRQVMFTVYVTSTPYDPLVTPVYTIS
FGGRVEVPQNCELNAGQIVEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAVKCTNVAAQ
AYLTMRLEASAVSGQAMVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLR
AWPISITGQKPTEGPFSALGYLRVDYQ