Protein Info for b0531 in Escherichia coli BW25113

Name: sfmC
Annotation: pilin chaperone, periplasmic (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00345: PapD_N" amino acids 26 to 145 (120 residues), 128.5 bits, see alignment E=1.5e-41 PF02753: PapD_C" amino acids 167 to 222 (56 residues), 41.6 bits, see alignment E=1.3e-14

Best Hits

Swiss-Prot: 100% identical to SFMC_ECOLI: Probable fimbrial chaperone SfmC (sfmC) from Escherichia coli (strain K12)

KEGG orthology group: K07353, fimbrial chaperone protein (inferred from 100% identity to eco:b0531)

Predicted SEED Role

"Fimbrial periplasmic chaperone SfmC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P77249 at UniProt or InterPro

Protein Sequence (230 amino acids)

>b0531 pilin chaperone, periplasmic (NCBI) (Escherichia coli BW25113)
MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTAVWIRNSHTNERFLVNS
WIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAADRESLFWMNVKTIPSVDKN
ALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSRSGNYINVHNPSPFYVTLVNL
QVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDYGSVTPVREVNLN