Protein Info for b0336 in Escherichia coli BW25113

Name: codB
Annotation: cytosine transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 52 to 74 (23 residues), see Phobius details amino acids 95 to 118 (24 residues), see Phobius details amino acids 128 to 147 (20 residues), see Phobius details amino acids 152 to 173 (22 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details amino acids 224 to 252 (29 residues), see Phobius details amino acids 259 to 278 (20 residues), see Phobius details amino acids 299 to 318 (20 residues), see Phobius details amino acids 324 to 345 (22 residues), see Phobius details amino acids 357 to 377 (21 residues), see Phobius details amino acids 383 to 402 (20 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 11 to 397 (387 residues), 289.1 bits, see alignment E=2.9e-90

Best Hits

Swiss-Prot: 100% identical to CODB_ECOL6: Cytosine permease (codB) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K10974, cytosine permease (inferred from 100% identity to eco:b0336)

MetaCyc: 100% identical to cytosine transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-116

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AA82 at UniProt or InterPro

Protein Sequence (419 amino acids)

>b0336 cytosine transporter (NCBI) (Escherichia coli BW25113)
MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLGTGLSYHDFFLAVLIGN
LLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPV
GKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPAIACLGGYSVWLAVNGMGGLD
ALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFGRNAKLAVLVAMVAFFLGNSLMF
IFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGMSSK
TLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPPVGGVIIADYLMNRRRYEHFATTRMMS
VNWVAILAVALGIAAGHWLPGIVPVNAVLGGALSYLILNPILNRKTTAAMTHVEANSVE