Protein Info for b0267 in Escherichia coli BW25113

Name: yagA
Annotation: CP4-6 prophage; predicted DNA-binding transcriptional regulator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 PF13518: HTH_28" amino acids 16 to 64 (49 residues), 46.6 bits, see alignment 1.1e-15 PF13384: HTH_23" amino acids 16 to 59 (44 residues), 37.8 bits, see alignment 5e-13 PF13011: LZ_Tnp_IS481" amino acids 20 to 73 (54 residues), 30.6 bits, see alignment 1.4e-10 PF13551: HTH_29" amino acids 23 to 75 (53 residues), 36.2 bits, see alignment 2.1e-12 PF13565: HTH_32" amino acids 43 to 116 (74 residues), 56.4 bits, see alignment E=1.5e-18 PF13276: HTH_21" amino acids 77 to 122 (46 residues), 29.3 bits, see alignment 3.3e-10 PF00665: rve" amino acids 139 to 241 (103 residues), 73.7 bits, see alignment E=5e-24 PF13683: rve_3" amino acids 230 to 295 (66 residues), 62.9 bits, see alignment E=7.7e-21

Best Hits

Swiss-Prot: 100% identical to YAGA_ECOLI: Uncharacterized protein YagA (yagA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b0267)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P37007 at UniProt or InterPro

Protein Sequence (384 amino acids)

>b0267 CP4-6 prophage; predicted DNA-binding transcriptional regulator (NCBI) (Escherichia coli BW25113)
MESLMPWDARDTMSLRTEFVLFASQDGANIRSLCRRFGISPATGYKWLQRWAQEGAAGLQ
DRPRIPHHSPNRSSDDITALLRMAHDRHERWGARKIKRWLEDQGHTMPAFSTVHNLMARH
GLLPGASPGIPATGRFEHDAPNRLWQMDFKGHFPFGGGRCHPLTLLDDHSRFSLCLAHCT
DERRETVQQQLVSVFERYGLPDRMTMDNGSPWGDTTGTWTALELWLMRLGIRVGHSRPYH
PQTQGKLERFHRSLKAEVLQGKWFADSGELQRAFDHWRTVYNLERPHEALDMAVPGSRYQ
PSARQYSGNTTPPEYDEGVMVRKVDISGKLSVKGVSLSAGKAFRGERVGLKEMQEDGSYE
VWWYSTKVGVIDLKKKSITMGKGC