Protein Info for b0055 in Escherichia coli BW25113

Name: djlA
Annotation: Dna-J like membrane chaperone protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 transmembrane" amino acids 6 to 31 (26 residues), see Phobius details PF05099: TerB" amino acids 62 to 170 (109 residues), 32.8 bits, see alignment E=7.7e-12 PF00226: DnaJ" amino acids 208 to 267 (60 residues), 40.8 bits, see alignment E=2e-14

Best Hits

Swiss-Prot: 100% identical to DJLA_ECOLI: Co-chaperone protein DjlA (djlA) from Escherichia coli (strain K12)

KEGG orthology group: K05801, DnaJ like chaperone protein (inferred from 100% identity to eco:b0055)

Predicted SEED Role

"DnaJ-like protein DjlA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P31680 at UniProt or InterPro

Protein Sequence (271 amino acids)

>b0055 Dna-J like membrane chaperone protein (NCBI) (Escherichia coli BW25113)
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFE
VMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRS
VCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQ
FGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAK
GLPPEMMEMAKQKAQEIQQAYELIKQQKGFK