Negative cofitness for PP_5271 from Pseudomonas putida KT2440

DNA-binding transcriptional dual regulator, leucine-binding
SEED: Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
KEGG: Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_1313 Transcriptional regulator, AraC family -0.19
2 PP_4484 histidine / lysine / arginine / ornithine ABC transporter - permease subunit -0.19
3 PP_2389 conserved protein of unknown function -0.18
4 PP_4486 lysine / arginine / ornithine ABC transporter - periplasmic binding protein -0.18
5 PP_4776 AsnC family transcriptional regulator -0.17
6 PP_1444 quinoprotein glucose dehydrogenase -0.17
7 PP_4947 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase -0.16
8 PP_5024 Amino acid ABC transporter, periplasmic amino acid-binding protein -0.16
9 PP_4485 histidine / lysine / arginine / ornithine ABC transporter - permease subunit -0.16
10 PP_1304 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase -0.15
11 PP_3957 choline/carnitine/betaine transporter BetTC -0.15
12 PP_2082 phosphoenolpyruvate synthetase -0.14
13 PP_0282 L-arginine ABC transporter - periplasmic binding subunit -0.14
14 PP_5273 putative Oxidoreductase -0.14
15 PP_4059 fused trehalose synthase B/maltokinase -0.14
16 PP_5639 conserved exported protein of unknown function -0.14
17 PP_4989 Protein PilJ -0.14
18 PP_2507 Oxidoreductase, short-chain dehydrogenase/reductase family -0.13
19 PP_1303 Sulfate adenylyltransferase subunit 2 -0.13
20 PP_2091 putative Serine/threonine-protein kinase -0.13

Or look for positive cofitness