Negative cofitness for PP_5085 from Pseudomonas putida KT2440

malic enzyme B
SEED: NADP-dependent malic enzyme (EC 1.1.1.40)
KEGG: malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+)

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_1444 quinoprotein glucose dehydrogenase -0.25
2 PP_3651 Sensor histidine kinase/response regulator -0.23
3 PP_5003 poly(3-hydroxyalkanoate) polymerase 1 -0.23
4 PP_1113 Pyridoxal-phosphate dependent enzyme family protein -0.23
5 PP_1761 diguanylate cyclase with phosphodiesterase domain -0.23
6 PP_4785 conserved exported protein of unknown function -0.22
7 PP_5053 Protein-export protein SecB -0.22
8 PP_4172 conserved exported protein of unknown function -0.22
9 PP_2437 putative Acyl-CoA dehydrogenase -0.21
10 PP_2387 conserved protein of unknown function -0.21
11 PP_4059 fused trehalose synthase B/maltokinase -0.21
12 PP_5005 Poly(3-hydroxyalkanoate) polymerase 2 -0.20
13 PP_5006 Transcriptional regulator, TetR family -0.20
14 PP_2712 conserved exported protein of unknown function -0.20
15 PP_1898 MotA/TolQ/ExbB proton channel family protein -0.19
16 PP_2098 D-alanyl-D-alanine carboxypeptidase -0.19
17 PP_4217 outer membrane ferripyoverdine receptor FpvA, TonB-dependent -0.19
18 PP_4171 conserved exported protein of unknown function -0.18
19 PP_4994 conserved protein of unknown function -0.18
20 PP_5283 periplasmic dipeptide transport protein -0.18

Or look for positive cofitness