Negative cofitness for PP_4977 from Pseudomonas putida KT2440

5,10-methylenetetrahydrofolate reductase
SEED: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
KEGG: methylenetetrahydrofolate reductase (NADPH)

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_1909		putative septum formation protein	-0.33
2	PP_1279		Probable alginate O-acetylase AlgJ	-0.33
3	PP_4946		sodium/L-proline transporter	-0.33
4	PP_0804		Protein secretion ABC efflux system, permease and ATP-binding protein	-0.33
5	PP_0803		Protein secretion ABC efflux system, membrane fusion protein	-0.32
6	PP_0806		putative Surface adhesion protein	-0.32
7	PP_0805		Outer membrane efflux protein	-0.32
8	PP_4872		putative enzyme of unknown function	-0.31
9	PP_3353		putative sulfatase-modifying factor (C-alpha-formyglycine- generating enzyme)	-0.31
10	PP_0137		glutamate/aspartate-proton DAACS transporter	-0.31
11	PP_5283		periplasmic dipeptide transport protein	-0.31
12	PP_1007		putative Transmembrane sensor	-0.30
13	PP_0287		conserved exported protein of unknown function	-0.30
14	PP_2362		putative usher protein	-0.29
15	PP_4892		integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex	-0.29
16	PP_2148		transcription-repair coupling factor	-0.28
17	PP_2096		fused 23S rRNA m2G2445 methyltransferase and 23S rRNA m7G2069 methyltransferase	-0.27
18	PP_1036		membrane-bound lytic murein transglycosylase F	-0.27
19	PP_1797		HlyD family secretion protein	-0.27
20	PP_2027		conserved exported protein of unknown function	-0.27

Or look for positive cofitness