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  • Negative cofitness for PP_4923 from Pseudomonas putida KT2440

    Outer membrane efflux protein
    SEED: Type I secretion outer membrane protein, TolC precursor
    KEGG: outer membrane channel protein TolC

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_2047 3-hydroxyacyl-CoA dehydrogenase family protein -0.38
    2 PP_2046 Transcriptional regulator, LysR family -0.30
    3 PP_4059 fused trehalose synthase B/maltokinase -0.23
    4 PP_1515 Transcriptional regulator, tetR family -0.20
    5 PP_5005 Poly(3-hydroxyalkanoate) polymerase 2 -0.20
    6 PP_5217 Polyphosphate kinase -0.18
    7 PP_4228 conserved protein of unknown function -0.18
    8 PP_1783 dTDP-glucose pyrophosphorylase -0.18
    9 PP_4051 malto-oligosyltrehalose trehalohydrolase -0.18
    10 PP_4398 Major facilitator family transporter -0.17
    11 PP_0065 NAD-binding component of TrK potassium transporter -0.17
    12 PP_1022 glucose 6-phosphate-1-dehydrogenase -0.17
    13 PP_3695 conserved protein of unknown function -0.16
    14 PP_2378 Fe/S biogenesis protein NfuA -0.16
    15 PP_1908 putative Peptidase -0.16
    16 PP_0918 putative 3-beta hydroxysteroid dehydrogenase/isomerase family protein -0.16
    17 PP_1362 pyruvate kinase II -0.15
    18 PP_0192 putative FKBP-type 25 kDa peptidyl-prolyl cis-trans isomerase -0.15
    19 PP_1453 putative NUDIX hydrolase with low 3-phosphohydroxypyruvate phosphatase activity -0.15
    20 PP_1918 septation protein -0.15

    Or look for positive cofitness