Negative cofitness for PP_4922 from Pseudomonas putida KT2440

Phosphomethylpyrimidine synthase
KEGG: thiamine biosynthesis protein ThiC

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_1783		dTDP-glucose pyrophosphorylase	-0.34
2	PP_4880		exoribonuclease R	-0.32
3	PP_4895		tRNA dimethylallyltransferase	-0.32
4	PP_0872		Peptide chain release factor 3	-0.31
5	PP_3831		conserved protein of unknown function	-0.31
6	PP_5310		junction-specific ATP-dependent DNA helicase	-0.31
7	PP_0719		ribosome-associated potassium-dependent informational ATP/GTPase	-0.29
8	PP_2210		LysR family transcriptional regulator	-0.29
9	PP_t11		tRNA-Lys	-0.28
10	PP_2387		conserved protein of unknown function	-0.28
11	PP_1529		Probable cysteine desulfurase	-0.27
12	PP_4542		putative ABC transporter, ATP-binding protein/permease protein	-0.27
13	PP_4902		Oligoribonuclease	-0.27
14	PP_0833		queuine tRNA-ribosyltransferase	-0.26
15	PP_4200		conserved exported protein of unknown function	-0.26
16	PP_2332		conserved exported protein of unknown function	-0.26
17	PP_4265		DNA-binding transcriptional dual regulator	-0.26
18	PP_4560		putative Ribonuclease BN	-0.25
19	PP_1527		tRNA threonylcarbamoyladenosine dehydratase (t(6)A37 dehydratase)	-0.25
20	PP_4892		integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex	-0.25

Or look for positive cofitness