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  • Negative cofitness for PP_4862 from Pseudomonas putida KT2440

    3-hydroxy acid dehydrogenase, NADP-dependent / malonic semialdehyde reductase
    SEED: Oxidoreductase, short chain dehydrogenase/reductase family

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_2907 DNA-binding response regulator -0.30
    2 PP_2716 arsenate reductase -0.22
    3 PP_5563 conserved membrane protein of unknown function -0.22
    4 PP_0274 putative transcriptional regulator containing HTH domain -0.21
    5 PP_2645 magnesium transporter, ATP-dependent -0.21
    6 PP_4342 flagellar synthesis regulator, putative ATPase -0.21
    7 PP_2379 putative cytochrome oxidase biogenesis protein -0.21
    8 PP_5337 LysR family transcriptional regulator -0.20
    9 PP_3050 conserved protein of unknown function -0.20
    10 PP_5133 conserved membrane protein of unknown function -0.20
    11 PP_4475 succinylglutamate desuccinylase -0.20
    12 PP_4590 conserved protein of unknown function -0.19
    13 PP_4305 sulfate ABC transporter -0.19
    14 PP_2567 Hydrolase, alpha/beta fold family -0.19
    15 PP_2689 putative Endoribonuclease -0.19
    16 PP_3551 DNA-binding response regulator, LuxR family -0.19
    17 PP_2122 molybdenum cofactor biosynthesis protein B -0.19
    18 PP_4946 sodium/L-proline transporter -0.18
    19 PP_3353 putative sulfatase-modifying factor (C-alpha-formyglycine- generating enzyme) -0.18
    20 PP_0137 glutamate/aspartate-proton DAACS transporter -0.18

    Or look for positive cofitness