Negative cofitness for PP_4830 from Pseudomonas putida KT2440

precorrin-6Y C(5,15)-methyltransferase
SEED: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
KEGG: precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_4946 sodium/L-proline transporter -0.30
2 PP_3353 putative sulfatase-modifying factor (C-alpha-formyglycine- generating enzyme) -0.27
3 PP_0137 glutamate/aspartate-proton DAACS transporter -0.26
4 PP_2379 putative cytochrome oxidase biogenesis protein -0.25
5 PP_4945 23S rRNA m(6)A2030 methyltransferase -0.24
6 PP_5580 protein of unknown function -0.24
7 PP_0287 conserved exported protein of unknown function -0.23
8 PP_0804 Protein secretion ABC efflux system, permease and ATP-binding protein -0.23
9 PP_0279 conserved protein of unknown function -0.23
10 PP_4927 Cyclolysin secretion/processing ATP-binding protein CyaB -0.22
11 PP_4118 putative Membrane protein -0.22
12 PP_0803 Protein secretion ABC efflux system, membrane fusion protein -0.22
13 PP_2741 conserved membrane protein of unknown function -0.21
14 PP_1577 Phage tail tape meausure protein, lambda family -0.21
15 PP_4583 putative Peptidase -0.21
16 PP_0267 putative Outer membrane ferric siderophore receptor -0.21
17 PP_2871 Class II aldolase/adducin domain protein -0.21
18 PP_5130 phosphoethanolamine/phosphocholine phosphatase -0.21
19 PP_3362 Transcriptional regulator, AsnC family -0.21
20 PP_0806 putative Surface adhesion protein -0.21

Or look for positive cofitness