Negative cofitness for PP_4778 from Pseudomonas putida KT2440

23S rRNA pseudouridine 2457 synthase
SEED: Ribosomal large subunit pseudouridine synthase E (EC 4.2.1.70)
KEGG: ribosomal large subunit pseudouridine synthase E

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_0987 L-serine dehydratase -0.16
2 PP_5014 Phosphoribosyl-AMP cyclohydrolase -0.16
3 PP_4453 glutathione ABC transporter ATP-binding subunit -0.15
4 PP_0083 tryptophan synthase beta chain -0.15
5 PP_2493 RadC family protein -0.15
6 PP_0421 Anthranilate phosphoribosyltransferase -0.14
7 PP_0486 Transcriptional regulator, GntR family -0.14
8 PP_4293 conserved exported protein of unknown function -0.14
9 PP_1986 3-isopropylmalate dehydratase small subunit -0.14
10 PP_1995 N-(5'-phosphoribosyl)anthranilate isomerase -0.14
11 PP_0082 tryptophan synthase alpha chain -0.13
12 PP_5098 methionine biosynthesis protein MetW -0.13
13 PP_4939 conserved protein of unknown function -0.13
14 PP_5676 conserved protein of unknown function -0.13
15 PP_2624 conserved protein of unknown function -0.13
16 PP_1988 3-isopropylmalate dehydrogenase -0.13
17 PP_5097 homoserine O-acetyltransferase -0.13
18 PP_1550 Transcriptional regulator, Cro/CI family -0.13
19 PP_0292 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) -0.13
20 PP_1952 Metallo-beta-lactamase family protein -0.13

Or look for positive cofitness