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  • Negative cofitness for PP_4778 from Pseudomonas putida KT2440

    23S rRNA pseudouridine 2457 synthase
    SEED: Ribosomal large subunit pseudouridine synthase E (EC 4.2.1.70)
    KEGG: ribosomal large subunit pseudouridine synthase E

    Computing cofitness values with 1005 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_0987 L-serine dehydratase -0.16
    2 PP_5014 Phosphoribosyl-AMP cyclohydrolase -0.15
    3 PP_4453 glutathione ABC transporter ATP-binding subunit -0.15
    4 PP_0083 tryptophan synthase beta chain -0.15
    5 PP_2493 RadC family protein -0.14
    6 PP_4293 conserved exported protein of unknown function -0.14
    7 PP_0421 Anthranilate phosphoribosyltransferase -0.14
    8 PP_0486 Transcriptional regulator, GntR family -0.14
    9 PP_3363 putative thymidylate kinase -0.13
    10 PP_1995 N-(5'-phosphoribosyl)anthranilate isomerase -0.13
    11 PP_4939 conserved protein of unknown function -0.13
    12 PP_0082 tryptophan synthase alpha chain -0.13
    13 PP_1986 3-isopropylmalate dehydratase small subunit -0.13
    14 PP_1550 Transcriptional regulator, Cro/CI family -0.13
    15 PP_1952 Metallo-beta-lactamase family protein -0.13
    16 PP_5676 conserved protein of unknown function -0.13
    17 PP_2624 conserved protein of unknown function -0.13
    18 PP_0833 queuine tRNA-ribosyltransferase -0.13
    19 PP_1125 putative Helicase -0.13
    20 PP_5098 methionine biosynthesis protein MetW -0.12

    Or look for positive cofitness